Postoperative lumbar intervertebral disc herniation Efficacy of methylprednisolone.doc

 PAGE \* MERGEFORMAT 3 Postoperative lumbar intervertebral disc herniation Efficacy of methylprednisolone Author: Chen Zefu Chu Wei-tao Dou Wei-Guo [Keywords:] lumbar disc herniation Efficacy of methylprednisolone In the lumbar disc herniation surgery are often due to stretch or irritate the nerve root caused by nerve root edema, further exacerbating the neurological symptoms. How to prevent and treat postoperative lumbar nerve root edema, is one of the challenges facing clinicians. In addition to operating in a gentle technique and try to avoid nerve stimulation, the drug treatment is also necessary. Steroids after spinal cord injury not only to reduce the secondary edema [1], but also in the prevention and treatment of lumbar disc herniation in patients with postoperative nerve root irritation caused by edema is also a significant effect. In the past used clinically with dexamethasone (DXM), the major adverse reactions were complicated by infection, and could easily cause a large dose of diabetes, peptic ulcer, and libraries Yan syndrome. The research and application of methylprednisolone (MP) treatment of 45 cases of lumbar disc herniation surgery patients and to achieve the desired effect. Report are as follows. 1 Materials and Methods 1.1 General information from March 2006 to October 2007, Jinyun County People’s Hospital were treated 95 cases of bone lumbar disc herniation patients, 64 patients were male, female 31 cases; the average (45.62 ± 7.31) years of age. Symptoms manifested in recurring low back pain or persistent back pain and sciatica with unilateral or bilateral lower extremity numbness; physical examination demonstrated lumbar scoliosis major disorders in intervertebral space next to the spinous process tenderness, lower extremity muscle strength decreased, feeling numb , straight leg raising test was positive and so on. All patients undergo CT or MRI examination diagnosis. Of which 4 cases with cauda equina nerve damage, manifested as s