PNS early stage patients with cerebral hemorrhage and plasma levels of MMP9 recovery of neurological function.doc

 PAGE \* MERGEFORMAT 12 PNS early stage patients with cerebral hemorrhage and plasma levels of MMP9 recovery of neurological function [Abstract] The purpose of acute treatment of cerebral hemorrhage improve circulation and provide a theoretical basis. Methods hospitalized within 24 h onset of 28 cases of cerebral hemorrhage were randomly divided into control group and treatment group, taken after onset 1,4,15 d blood test matrix metalloproteinase 9 (MMP 9 levels, and within 24 h after onset, 15,28 d neurological (CSS) score. Results Plasma levels of MMP 9 in the pathogenesis of the time 4 d significantly increased when compared with 1 d ( P lt;0.05, when the onset of 15 d significantly decreased when compared with 4 d treatment group, plasma levels of MMP 9 in the 4,15 d were significantly lower than the control group during (P lt;0.05. the two groups of patients with neurological score 15 d after the onset of with no noticeable difference compared with that before treatment, compared with differences between the two groups was not significant (Pgt; 0.05, 28 d after the onset of neurological function when the treatment group was significantly lower than the control group (P lt;0.05. Conclusions Cerebral hemorrhage Plasma levels of MMP 9 are dynamic, the incidence of 4 d 1 d higher than the incidence of, 15 d when the drop. PNS Early treatment of acute cerebral hemorrhage, can reduce the plasma levels of MMP 9 and reduce the secondary brain injury after intracerebral hemorrhage edema and promote recovery of neurological function. [Keywords:] cerebral hemorrhage, hematoma, matrix metalloproteinase, PNS Cerebral hemorrhage occurs in and around a series of pathological and physiological changes, and its mechanism of secondary injury are many, now that the surrounding intracerebral hemorrhage ischemia, cerebral edema are the mechanisms of secondary injury one. domestic and international research shows that the plasma matrix metalloproteinase 9 (MMP 9 concen