Proteasome inhibitor-based pharmacological and clinical application of.docVIP

 PAGE \* MERGEFORMAT 14 Proteasome inhibitor-based pharmacological and clinical application of [Keywords:] proteasome inhibitor; cancer; treatment [Abstract] proteasome inhibitors are a class through the ubiquitination pathway blocked by a new class of anticancer drugs, for cancer treatment has good application prospects. Proteasome is widely distributed in eukaryotic cytoplasm and nucleus, with a variety of functions protease complex, while the ubiquitin - proteasome system is the creatures selective degradation of proteins is one important way, these proteins, including transcription