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Progress in neonatal hyperglycemia
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Progress in neonatal hyperglycemia
Keywords:: Neonatal hyperglycemia
Over the past 10 years, the clinical course of treatment, a variety of high-risk newborns for glucose intolerance lead to high incidence of blood glucose and its potential impact on the brain damage has been more and more attention, this article on the clinical and neonatal blood glucose experimental research are reviewed.
The incidence of neonatal blood glucose
The incidence of neonatal hyperglycemia with a number of factors, such as the intravenous glucose solution supplement dose (concentration and speed), neonatal gestational age, birth weight, age, severity of the disease and stress status. Cowett of 35 healthy children with low birth weight intravenous glucose supplementation, 14mg/kg per minute all of those who experience high blood sugar. But to the weight of infants less than 1000g enter 10% of the glucose dose of 8.4mg/kg. min, the incidence of high blood sugar 29%, the same doses used in birth weightamp;gt; 2000g infants, the incidence of high blood sugar was only 1.6% (1). Xiaolin Ouyang and other 74 cases of neonatal hypoxic-ischemic encephalopathy in the treatment of pre-testing of the blood sugar, of which 5 cases had a high blood glucose, incidence of 6.8% (2). Li Jiu-jun and other reports for various reasons, the hospital NICU neonatal transient hyperglycemia incidence of 6% to 8% (3). Stress state of the baby itself may be the presence of high blood sugar, glucose tolerance did not stifle the newborns were 34.7% glucose intravenous infusion of high blood sugar occurs (4). More severe degree of asphyxia, blood glucose increased more obvious (5).
Etiology and mechanism of neonatal hyperglycemia
1, iatrogenic hyperglycemia unjustified iatrogenic neonatal glucose solution is a major cause of high blood sugar. Caused by high blood sugar sugar-dose intravenous great individual differences, and neonatal birth weight, gestational age, and stress related.
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