Pseudomonas aeruginosa clinical isolates resistant to cefotaxime Analysis_0.docVIP

 PAGE \* MERGEFORMAT 11 Pseudomonas aeruginosa clinical isolates resistant to cefotaxime Analysis Of: Lu Rong Zhou Liming Shaozhen Jun Yang Wenji [Abstract] Objective: To determine the Pseudomonas aeruginosa resistant to cefotaxime. Methods: The agar dilution method for the determination of copper and aluminum Pseudomonas cefotaxime MIC values. With the standards of Pseudomonas aeruginosa ATCC27853 strain as a quality control standard. According to the U.S. clinical trials Standards Committee (NCCLS2004 standards promulgated in the operation and determine the results. Results: Pseudomonas aeruginosa resistant to cefotaxime was 59.18%. Conclusion: The clinical isolates of Pseudomonas aeruginosa cell strains highly resistant to cefotaxime should be considered by the bacterial culture and sensitivity test, rational use of antibiotics, or use a synergistic effect of the two combination therapy to improve efficacy against Pseudomonas aeruginosa infection. [Keywords:] Pseudomonas aeruginosa, cefotaxime, drug resistance Pseudomonas aeruginosa (Pseudomonas aeruginosa) is a non-fermenting oxidase-positive gram-negative bacteria, is the most common opportunistic pathogen of clinical. With antibiotics and some of the medical technology widely used in clinical, clinical and antibiotic prophylaxis unreasonable application of bacteria growing drug resistance [1]. and cefotaxime (cefetaxime is a third generation cephalosporin with broad-spectrum, low toxicity, high efficiency, enzyme-resistant characteristics of Gram-negative bacteria have a strong antibacterial effect. But with the widespread use of the drug, resistant bacteria growing. for the study of Pseudomonas aeruginosa to cefotaxime resistance to the rational use of antibiotics for clinical reference, is determined for 49 clinical isolates in our hospital strains of Pseudomonas aeruginosa to cefotaxime minimum inhibitory concentration (MIC), analysis of cefotaxime resistance. 1 Materials and methods