Purification of compound Dragon Ning Pill Study.doc

 PAGE \* MERGEFORMAT 7 Purification of compound Dragon Ning Pill Study Of: Hao Jianping Sun Jing Wang Changli Suzhuo, Zhu Ling [Abstract] Objective To further improve the compound through experiment Root Pills purification process parameters rather, for the preparation lay the foundation for industrial production. Methods puerarin as index by thin layer chromatography and high performance liquid chromatography and their contents, on AB-8 macroporous resin and purification of the preparation purified experimental prescription. Results by adsorption - elution of the purification method is more dynamic and reasonable 3BV required to elute 70% ethanol completely. Conclusions The purification process parameters are reasonable, convenient and reproducible. AB-8 macroporous resin has good purification effect, can effectively removing impurities, thus reducing dose while maintaining efficacy of pharmaceutical preparations. [Keywords:] compound Dragon Ning, purification process, puerarin Medicinal pills by suitable means to extract, purification, concentration and substrate with the appropriate melt mixing, the instillation of immiscible condensate, condensation and contraction of a spherical or sphere made preparations [1] . Compound Ning pills from the Pueraria Root, Dioscorea nipponica extract of 4 herbs processed with Tongluo blood circulation, anti-inflammatory role of stasis, for the treatment of stroke caused by hemiplegia, numbness, chest tightness caused by Kouyanwaixie and Chest , heart palpitations, shortness of breath embolism. The preparation of basic research is relatively mature, through two years of experimental research has been high repeatability, more scientific and rational extraction process parameters. In order to reduce the dose, the compound was a large hole Purification of experimental study, prepared by purification pills taking is greatly reduced, the initial observation of the pharmacodynamics of the agents with better therapeutic