Qi rat heart and cardiac ultrastructure of free radical damage.docVIP

 PAGE \* MERGEFORMAT 11 Qi rat heart and cardiac ultrastructure of free radical damage OF: TRADITIONAL YAO Xia Yu-Tang Ye Fu Gong Wenbo [Abstract] Objective: To observe the free radical damage heart deficiency and myocardial ultrastructure in rats. Methods: Adult inbred Wistar rats were 26, were randomly divided into control group and 12 observation group, 14 rats, the observed deficiency model group were measured after the heart made of serum superoxide dismutase (SOD and malondialdehyde (MDA content and myocardial ultrastructure with transmission electron microscopy. Results: The SOD group than in control group (P lt;0.01) , MDA higher (P lt;0.01), observed myocardial cell damage, muscle disorder, mitochondrial swelling, structural fuzzy, cristae are dissolved. Conclusions: Myocardial damage may lead to cardiac ultrastructural deficiency causes while the injury may be related to free radicals. [Keywords:] Heart Qi, free radicals, myocardial ultrastructure Abstract Objective: To observe the damage to free radical and ultramicrostructure of heart muscle in the rats with deficiency of heart-energy. Methods: 26 adult inbreeding line Wistar rats were divided into the control group (12 rats) and the model group (14 rats ). After preparing animal model of deficiency of heart-energy with the rats from the model group. SOD and MDA was measured, and heart muscle ultramicrostructure was observed as well by electron microscope. Results: SOD of swimming model group was lower than that in the control group (P lt;0.01). MDA of swimming model group was higher than that in the control group (P lt;0.01). ultramicrostructure of heart muscle was damaged in the rats from the model group. Conclusion: The damage to heart muscle ultramicrostructure may be chiefly responsible fro deficiency of heart-energy, and its damaging mechanism seems to be related to free radical. Keywords: Deficiency of heart-energy, Free radical; Heart muscle ultramicrostructure Currently, c