Qianlieantong tablets on norepinephrine-induced contraction of isolated rabbit deltoid muscle of the bladder_0.docVIP

 PAGE \* MERGEFORMAT 9 Qianlieantong tablets on norepinephrine-induced contraction of isolated rabbit deltoid muscle of the bladder [Abstract] Objective To observe the forefront of the safety of antispasmodic tablets. Methods 12 rabbits were randomly divided into 2 groups, one circular muscle slice preparation, a group of longitudinal muscle preparation of tablets. To norepinephrine (NE) induced contraction of the deltoid muscle were observed effect of 6 groups of drugs, that is the forefront of the security tablets high, medium and low dose group and high Trane group, control group, Tween -80 group. Results Qianlieantong tablets can inhibit NE induced contraction of isolated bladder deltoid muscle (including circular muscle and longitudinal muscle), inhibition was positively correlated with the concentration, the higher Trane weak. Conclusion Qianlieantong significant spasm tablets to improve due to benign prostatic hyperplasia bladder outlet obstruction, benign prostatic hyperplasia effectively alleviate the dynamic factors. [Keywords:] Qianlieantong tablets, spasm, benign prostatic hyperplasia, rabbit Abstract: Objective To observe spasmolytic effect of Qianlieantong tablets. Methods Twelve rabbits were randomly divided into 2 groups. One group was to prepare ring muscles, another was to prepare longitudinal muscles. Contraction of trigone muscle was induced by NE. Effects of 6 groups drug were observed, which were high, middle and low concentration Qianlieantong group, Hytrine group, blank group, Tween 80 group (TW-80). Results Qianlieantong tablets can significantly inhibit contraction of NE-inducted rabbit trigone muscle (including ring and longitudinal muscles) in vitro, and the inhibition was positively correlated with concentration, which was less than Hytrine. Conclusions Qianlieantong tablets had spasmolytic effect of alleviating BPH-induced badder outlet obstruction and reducing dynamic factors caused by BPH. Keywords:: Qianlieantong tab