Pulmonary contusion comprehensive prevention and treatment of early acute lung injury prognosis of patients.docVIP

 PAGE \* MERGEFORMAT 17 Pulmonary contusion comprehensive prevention and treatment of early acute lung injury prognosis of patients Keywords:: pulmonary contusion [Abstract] Objective To analyze and summarize the early comprehensive prevention and treatment of severe pulmonary contusion prognosis of patients with acute lung injury. Methods Retrospective analysis of 54 cases of acute lung injury in patients with severe pulmonary contusion clinical data, the selected patients within 48h after injury, diagnosed according to the disease or not divided into 2 groups, the early treatment group (treatment group): 26 cases, control group: 28 cases . Group 2 In addition to disposal of the original trauma, early mechanical ventilation, oxygen, anti-infection and bleeding conventional treatment, the diagnosis of this disease in time after the adoption of comprehensive prevention and treatment programs (methylprednisolone 250 ~ 500mg, albumin 10g, furosemide 20mg , Ulinastatin 200,000 U NS 20ml, 1 to 2 times intravenously. Ambroxol 30mg, day three times intravenously, early enteral nutrition, a reasonable capacity to support), Investigation and Analysis of the prognosis of two groups. The results of two age groups (42.9 ± 13.89/39.92 ± 19.37) years, admission PaO2 (68.4 ± 15.76/67.63 ± 15.01mmHg), PaCO2 (31.97 ± 5.54/28.26 ± 5.29mmHg), APACHE Ⅱ score (18.38 ± 3.2/19.5 ± 16.76) there was no significant difference (P all amp;quot;0.05). Comprehensive prevention and treatment programs treatment group, PaO2 increased after 24h treatment (91.88 ± 14.79mmHg) were significantly higher (73.99 ± 14.67mmHg) (P amp;lt;0.001). Treatment of the final result, the treatment group ARDS, MODS, ventilator-associated pneumonia incidence and mortality rate (15.2% / 7.69% / 7.69% / 3.85%) was significantly lower than the control group (64.3% / 35.71% / 30.77% / 30.77% ) (P amp;lt;0.05 / P amp;lt;0.025 / P amp;lt;0.05 / P amp;lt;0.05). Use the number of ventilator days (7.38 ± 2.6