Quality standard of warts granule.docVIP

 PAGE \* MERGEFORMAT 10 Quality standard of warts granule [Abstract] Objective To establish a quality control of particle clearance of warts. Methods TLC preparation Cyperus rotundus, white peony root qualitative identification of the active ingredient group astragaloside Fang reversed-phase high performance liquid chromatography - evaporative light scattering detection (RP-HPLC-ELSD) for quantitative analysis. Results TLC spots were clear and easy to identify, RP-HPLC-ELSD method precision, reproducibility, astragaloside range of 1.032 ~ 5.16 μg with a more good linear relationship, the average recovery was 99.051 6%, RSD = 1.05%. Conclusions In this study, developed on the basis of quality standards to control the intrinsic quality of the product, the method is feasible. Keywords:] warts granule, astragaloside, high performance liquid chromatography - evaporative light scattering detection method, thin layer chromatography Abstract: Objective To establish the quality control method for Youqing Granules. Methods Qualitation discrimination of Rhizoma Cyperi and Raidix Paeoniae in this formula was identified by TLC. Quantitive analysis of Astragaloside A which is the effective element of the formula was adopted by RP-HPLC- ELSD. Result The specks in TLC were clear and easy to discriminate. The precision and reproducibility of the RP-HPLC-ELSD method were fine. In 1.032 ~ 5.16 μg, the content of Astragaloside A had good linear relationship. The average recovery rate of sample was 99.051 6%, and RSD = 1.05%. Conclusion The quality standard established on this study can control the quality of the products, the method is viable. Key word: Youqing Granules, Astragaloside A, RP-HPLC-ELSD, TLC Warts granule from Astragalus, white peony root, Cyperus rotundus, Coix seed and other drug composition, with heat and detoxifying, care drugs abscess, sore myogenic effect of convergence, mainly for the treatment of genital warts and other skin diseases. In this e