r-glutamyl GGT alkaline phosphatase tumor necrosis factor detection of liver cancer the diagnosis of chronic liver disease.doc

 PAGE \* MERGEFORMAT 5 r-glutamyl GGT alkaline phosphatase tumor necrosis factor detection of liver cancer the diagnosis of chronic liver disease [Abstract] Objective To investigate the r-glutamyl GGT (r-GT), alkaline phosphatase (ALP), tumor necrosis factor (TNF) detection of liver disease. Methods were used to rate method, double antibody sandwich Method 168 patients with various liver diseases on serum r-GT, ALP, TNF were detected and 110 cases with the control healthy subjects. Results HCC patients r-GT, ALP were significantly higher than that of liver cirrhosis, hepatitis, higher in the control group, all patients with liver disease were significantly higher than TNF control. Conclusions The serum r-GT, ALP, TNF combined detection of liver cancer, cirrhosis, hepatitis diagnosis of greater clinical value. [Keywords:] r-glutamyl GGT, alkaline phosphatase, tumor necrosis factor, liver In recent years, the r-glutamyl GGT (r-GT) is a precancerous tumors in experimental animals and the earlier stages of tumor marker enzyme in the pathology has been widely used as a marker of liver cancer, at home and abroad have It has been reported [1]. Tumor necrosis factor (TNF) is an important immune system component, it is by peripheral blood mononuclear cells and macrophages produced cytokines, have anti-tumor, anti-infection and other biological activities , is the research focus of cytokines. But r-GT, alkaline phosphatase (ALP), TNF and is used for combined detection of hepatocellular carcinoma (HCC), few reports on the diagnosis of chronic hepatitis. Based on the detection of 168 patients with various liver diseases r-GT, ALP, TNF, to further explore the diagnostic value of liver disease, are as follows. 1 Materials and methods 1.1 Test objects We selected 168 patients with various types of liver disease, including HCC 71 cases of liver cirrhosis (LC) 32, chronic active hepatitis (CAH) 65 cases, 110 cases of healthy people as control group. 1.2 Det