Return bar plate extracts against herpes simplex virus-I type of pharmacological effects of_0.doc

 PAGE \* MERGEFORMAT 9 Return bar plate extracts against herpes simplex virus-I type of pharmacological effects of Of: Zhang Changcheng, Huang Hefei Zhou Zhiyong, Yuan Ding [Abstract] Objective To study extracts from the bar board go against herpes simplex virus -1 (HSV-1) the role of board of bar owned by the pharmacological effects of anti-herpes virus and effective parts. Approach chromatography using solvent and go from the bar board extract isolated from four sites, MTT assay plate bar owned by different extracts of viral suppression to viral suppression rate and therapeutic index (TI) as the evaluation index, compare different parts of in vitro antiviral effect. Results normalized alcohol bar board macroporous resin extract sites and antiviral activity of the strongest parts of alcohol to wash the drug concentration in the 8 μg · ml-1 above, the inhibition of HSV up to 50% or more, with the positive control drug acyclovir no significant difference (Pgt; 0.05). Conclusion bar owned by extracts board has good anti-HSV-1 function, its active ingredient is flavonoids, with further research and development value. [Keywords:] bar board return; Herpes simplex virus -1; effective parts Return line for the bar board of Polygonum Polygonaceae Polygonaceae plants owned by Polygonum perfoliatum L. bar plate of fresh or dried whole plant, also known as Hypericum capitatum, with detoxification, expectorant cough, dampness swelling, bleeding and other effects Sanyu , attending carbuncle swollen boils, erysipelas, etc., only contained in the lt;lt;million patients Rejuvenationgt;gt;. folk conventional bar plate of fresh goods or dry goods go mash topical treatment of herpes zoster and other diseases, with good results. Modern pharmacological studies have shown that , bar board go with the anti-inflammatory, antibacterial, anti-tumor activity [1,2]. current bar classified board less antiviral activity, some of its pharmacological activity and the active ingred