Rhubarb and its active ingredient on the cardiovascular system.doc

 PAGE \* MERGEFORMAT 12 Rhubarb and its active ingredient on the cardiovascular system Author: Tan Xiaohong ZHANG Dan Zhang Shu-Hua Jiang Hua-fang Wang [Keywords:] Rhubarb Rhubarb (rhubarb), also known as Huang Liang, fire ginseng, cotton stripes, Joseph, Department of Polygonum Rheum palmatum (Rheum palmatum L.), tanguticum (R.tanguticum Maxim.ex Reg.) And medicinal rhubarb (R . officinale Baill.) dry root and rhizome of rhubarb as a perennial herb in China are distributed in many parts. Rhubarb has been clinically used drugs, according to ‘Shen Nong Ben Cao Jing’ record: Rhubarb has a ‘master under the stasis of blood closed cold and heat, breaking Zhengjia accumulation, leaving drink Sushi, and cleaned up the stomach, pushing Chen Zhixin, Tom Lee Water Valley, transfer Sinochem food, peaceful and five internal organs’ [1] effect. From the previous century, many scholars studied the active ingredients of rhubarb [2,3,4,], that its main active ingredients are: anthraquinones and rhubarb tannins glycosides. At present, the pharmacological effects of the active ingredients of rhubarb study focused on anthraquinone compounds, including free anthraquinones such as: rhubarb phenols, rhein, emodin, emodin ether, rhubarb alcohol, aloe-emodin, etc.; as well as the combination of anthracene quinone derivatives such as: double-and single-anthrone glycosides glycosides addition, rhubarb also contains large amounts of lecithin, β -sitosterol and polysaccharides. Early Chinese pharmacological studies have shown that rhubarb has a bleeding, catharsis, antibacterial and so on. In recent years, rhubarb at home and abroad, particularly in the pharmacological effects of its active ingredients conducted in-depth study. In this paper, rhubarb and the active ingredient in cardiovascular pharmacology research to make a brief: An anti-ischemic effects of rhubarb and its active ingredient through the anti-thrombosis, anti-coronary artery spasm, either directly or indirectly, such