Shenqitang intervention of restenosis after coronary stent implantation in clinical research.docVIP

 PAGE \* MERGEFORMAT 33 Shenqitang intervention of restenosis after coronary stent implantation in clinical research Of: Zhaohua Yun, Wang will, Lang Jiang Ming, Chan Wai Keung, Luo Zixing, Yu Xiulan, He Qingjun [Abstract] Objective To observe the seven participating stent Coronary heart disease inflammatory immune response, immune status, and restenosis, and to explore its mechanism. Methods in patients with coronary stent implantation, 88 cases randomized, control method is divided into 45 cases of the treatment group and control group of 43 patients. Western conventional treatment control group, treatment group, in its based on the use of Shenqitang, for 6 months to observe the incidence of restenosis, high sensitive C-reactive protein (hsCRP), activated T lymphocytes (CD3 + / HLA-DR +), soluble interleukin -2 receptor (SIL-2R), and blood stasis, qi deficiency points. restenosis rate in the treatment group than the control group ( P lt;0.05). Percutaneous Coronary Intervention, CD3 + / HLA-DR + compared with preoperative lower, SIL-2R, hsCRP increased compared with that before, after treatment, CD3 + / HLA-DR + levels higher than the control group (P lt; 0.01), SIL-2R, hsCRP levels lower than the control group (P lt;0.01), integral gas deficiency blood stasis points were significantly lower than the control group (P lt;0.01), and lasted until after 6 months. Conclusions Participation Seven soup can effectively reduce coronary restenosis after interventional treatment. to reduce stent induced inflammatory immune responses and regulate immune status, is the prevention of restenosis after percutaneous coronary intervention mechanism. [Keywords:] Shenqitang; coronary heart disease; in-stent restenosis; inflammatory immune response; T lymphocyte activation Abstract: Objective To observe the effect of Shenqi Decoction on inflammation and immune reaction, immune state, restenosis (RS) after implantation of stents in patients with coronary artery disease