Tom Zhigancao deficiency of both qi and blood serum levels of cardiac arrhythmias and myocardial enzyme in the inflammatory cytokines_0.docVIP

 PAGE \* MERGEFORMAT 23 Tom Zhigancao deficiency of both qi and blood serum levels of cardiac arrhythmias and myocardial enzyme in the inflammatory cytokines Of: Chenlan Ying, Luo Xiong, Luo Yingying, Hurui Gang, Gong Qin, Chen Xiao, Chen Qi [Abstract] Objective Zhigancao deficiency of both qi and blood soup arrhythmias in rats. Methods and cyclophosphamide in the blood causing blood deficiency in rats on the basis of amount of sublingual intravenous aconitine, copy arrhythmia model in rats with deficiency of both qi and blood and used to prevent and treat Zhigancao soup, soup observed on rats Zhigancao ECG and serum enzymes and serum inflammatory cytokines sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-@ (TNF-@), interleukin -2 (IL-2), interleukin -6 (IL-6) levels. Results Zhigancao Decoction can improve the model rats ECG, prolonged latency and reduced arrhythmia arrhythmia maintenance phase; significantly higher in rats hs-CRP, TNF-@, IL-2 and IL-6 levels were significantly reduced myocardial enzyme CK and LDH levels. Conclusions Zhigancao deficiency of both qi and blood soup arrhythmia in rats may be related to improvement of myocardial cells mediated inflammation and myocardial enzyme activity. [Keywords:] Zhigancao soup; arrhythmia; blood deficiency; serum inflammatory factors; enzyme Abstract: ObjectiveTo study the protective action of Zhigancao Decoction on arrhythmia with deficiency of both “Qi” and blood in rats.MethodsOn the basis of syndrome of both “Qi” deficiency and blood deficiency in rats induced by bloodletting and cyclophosphamide, arrhythmia was induced by aconitine, and Zhigancao Decoction was used to prevent and treat arrhythmia rats with syndrome of deficiency of both “Qi” and blood.The changes of ECG were observed, and activities of hs-CRP, TNF-a, IL-2, IL-6 , CK and LDH were determined. Results Zhigancao Decoction could improve the ECG, increase arrhythmia latency and decrease arrhythmia duration significantl