Collision tumor of the thyroid follicular variant of papillary carcinoma and squamous carcinoma.docVIP

World Journal of Surgical Oncology BioMedCentral Case report Open Access Collision tumor of the thyroid: follicular variant of papillary carcinoma and squamous carcinoma Rohan R Walvekar1, Subhadra V Kane2 and Anil K DCruz*1 Address: 1Department of Head and Neck Surgery, Tata Memorial Hospital, Mumbai, India and 2Department of Pathology, Tata Memorial Hospital, Mumbai, India Email: Rohan R Walvekar - rrohanw@; Subhadra V Kane - drsvkane@; Anil K DCruz* - docdrcuz@ * Corresponding author Published: 19 September 2006 Received: 29 January 2006 Accepted: 19 September 2006 World Journal of Surgical Oncology 2006, 4:65 doi:10.1186/1477-7819-4-65 This article is available from: /content/4/1/65 ? 2006 Walvekar et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Collision tumors of the thyroid gland are a rare entity. We present a case of a follicular variant of papillary carcinoma and squamous carcinoma in the thyroid. To the best of our knowledge, this is the first documentation of a collision tumor with a papillary carcinoma and a squamous carcinoma within the thyroid gland. The clinicopathological features and immunohistochemical profile are reported. The theories of origin, epidemiology and management are discussed with a literature review. Case presentation: A 65 year old woman presented with a large thyroid swelling of 10 years duration and with swellings on the back and scalp which were diagnosed to be a follicular variant of papillary thyroid carcinoma with metastasis. Clinical examination, radiology and endoscopy ruled out any other abnormality of the upper aerodigestive tract. The patient was treated surgically with a total thyroidectomy with cent