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Combining partial liver resection and local ablation of liver tumours a preliminary Dutch experience.doc

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Combining partial liver resection and local ablation of liver tumours a preliminary Dutch experience

World Journal of Surgical Oncology BioMedCentral Research Open Access Combining partial liver resection and local ablation of liver tumours: a preliminary Dutch experience Bram Fioole1, Maarten C Jansen2, Frederieke H van Duijnhoven3, Richard van Hillegersberg1, Thomas M van Gulik2 and Inne HM Borel Rinkes*1 Address: 1Department of Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands, 2Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands and 3Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands Email: Bram Fioole - bfioole@planet.nl; Maarten C Jansen - m.c.jansen@amc.uva.nl; Frederieke H van Duijnhoven - f.h.van_duijnhoven@lumc.nl; Richard van Hillegersberg - r.vanhillegersberg@umcutrecht.nl; Thomas M van Gulik - t.m.vangulik@amc.uva.nl; Inne HM Borel Rinkes* - i.h.m.borelrinkes@umcutrecht.nl * Corresponding author Published: 17 July 2006 Received: 18 April 2006 Accepted: 17 July 2006 World Journal of Surgical Oncology 2006, 4:46 doi:10.1186/1477-7819-4-46 This article is available from: /content/4/1/46 ? 2006 Fioole et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The combination of partial liver resection and radiofrequency ablation (RFA) is a novel concept in the treatment of unresectable liver malignancies. The aim of this study is to evaluate the results of this combined strategy in the Netherlands. Methods: Thirty-five patients treated with a combination of partial liver resection and RFA were identified from a prospectively registered pooled multicentre database. All patients were operated between June 1999 and November 2003 in 8 medical centres in the Netherlands. Main outcome parameters were morbidit