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Combined use of preoperative 18F FDG-PET imaging and intraoperative gamma probe detection for accurate assessment of tumor recurrence in patients with colorectal cancer.doc

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Combined use of preoperative 18F FDG-PET imaging and intraoperative gamma probe detection for accurate assessment of tumor recurrence in patients with colorectal cancer

World Journal of Surgical Oncology BioMedCentral Research Open Access Combined use of preoperative 18F FDG-PET imaging and intraoperative gamma probe detection for accurate assessment of tumor recurrence in patients with colorectal cancer Ismet Sarikaya*1, Stephen P Povoski2, Osama H Al-Saif2, Ergun Kocak2, Mark Bloomston2, Steven Marsh1, Zongjian Cao3, Douglas A Murrey2, Jun Zhang1, Nathan C Hall1, Michael V Knopp1 and Edward W Martin Jr2 Address: 1Division of Nuclear Medicine, Section of PET, Department of Radiology, The Ohio State University, Columbus, OH 43210, USA, 2Division of Surgical Oncology, Department of Surgery, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA and 3Department of Radiology, Medical College of Georgia, Augusta, GA 30912, USA Email: Ismet Sarikaya* - ismet.sarikaya@; Stephen P Povoski - stephen.povoski@; Osama H Al- Saif - osama.alsaif@; Ergun Kocak - ergun.kocak@; Mark Bloomston - mark.bloomston@; Steven Marsh - steven.marsh@; Zongjian Cao - zcao@; Douglas A Murrey - duglas.murrey@; Jun Zhang - zhang.538@; Nathan C Hall - nathan.hall@; Michael V Knopp - michael.knopp@; Edward W Martin - edward.martin@ * Corresponding author Published: 16 July 2007 Received: 15 May 2007 Accepted: 16 July 2007 World Journal of Surgical Oncology 2007, 5:80 doi:10.1186/1477-7819-5-80 This article is available from: /content/5/1/80 ? 2007 Sarikaya et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The purpose of this study was to combine intraoperative gamma probe (GP) detection with preoperative fluorine 18-fluoro-2-deoxy-glucose positron emission tomography (18F FDG-PET) imaging in o