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BiologicalModelsofSecurityforVirusPropagationin
Biological Models of Security for Virus Propagation
in Computer Networks
Sanjay Goel Stephen F. Bush
Abstract
This article discusses the similarity between propag ation of pathoge ns (viruses and worms) on computer networks with
prolife ration of pathogens in cellular organisms (org anisms with genetic material contained within a membrane encased
nucleus). It intro duces several biological mechanisms that are used in these orga nisms to protect against suchpathog ens
andpre sents security models for networked comp uters inspired by biological paradig ms. Models for computer security can
be based on several different biolog ical paradigms, including, genomics (RNA Interference), proteomics (pathway
mapping) a ndp hysiology (Im mune System). In a ddition, the study of dise ase control under the rubric of epidemiological
models can inspire models for controlling the spread of pathogens across multiple nodes of a network. The pape r discusses
these models and presents results based on the authors’ research in immune system modeling.
Introduction
The analogy of computers and communication networks with living organisms is an enticing paradigm that
researchers have been exploring for some time. Fred Cohen (1984) first put the word “computer virus” into
print, although within the paper he credits Len Adleman with coining the term used to describe the malicious
pieces of code that can proliferate on a network and infect disparate computers. Since then, advances in
bioinformatics1 have helped to more precisely define these analogies to the point where results in
bioinformatics can often be leveraged for use in computer networking and security. The challenges faced in
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