河北唐山063000).PDFVIP

牛痘疫苗致炎兔皮提取物注射液联合阿昔洛韦治疗老年带状疱疹的临床观察 ＊ 刘国海 ，张贵田，刘庆明（唐山市工人医院皮肤科，河北唐山 063000） + 中图分类号 R752.12 文献标志码 A 文章编号 1001-0408（2013）16-1491-02 DOI 10.6039/j.issn. 1001-0408.2013.16.13 摘 要 目的：观察牛痘疫苗致炎兔皮提取物注射液联合阿昔洛韦治疗老年带状疱疹的疗效和安全性。方法：将120例患者均分 成治疗组和对照组，治疗组给予牛痘疫苗致炎兔皮提取物注射液、阿昔洛韦、维生素B 、维生素B 联合治疗；对照组给予阿昔洛 1 12 韦、维生素B 、维生素B 常规治疗，观察两组止疱时间、止痛时间、结痂时间、痊愈时间；并于治疗前及治疗第3、7、10天进行疼痛 1 12 视觉模拟评分（VAS ）评价，治疗过程中观察患者不良反应发生情况。结果：治疗组的止疱时间、止痛时间、结痂时间、痊愈时间、 VAS 评分等方面均优于对照组（P ＜0.05）。两组均未见明显不良反应发生。结论：牛痘疫苗致炎兔皮提取物注射液联合阿昔洛韦 治疗老年带状疱疹疗效较好、安全性较高，可明显减少后遗神经痛。 关键词 老年人；带状疱疹；牛痘疫苗致炎兔皮提取物注射液；阿昔洛韦 Clinical Observation of Extracts from Rabbit Skin Inflamed by Vaccinia Virus for Injection Combined with Acyclovir in the Treatment of Senile Herpes Zoster LIU Guo-hai ，ZHANG Gui-tian ，LIU Qing-ming （Dept. of Dermatology ，Tangshan Workers ’Hospital ，Hebei Tangshan 063000，China ） ABSTRACT OBJECTIVE ：To observe therapeutic efficacy and safety of Extracts from rabbit skin inflamed by vaccinia virus for injection （analgecine）combined with acyclovir in the treatment of senile herpes zoster. METHODS ：120patients were randomly di- vided into treatment group and control group ；treatment group received analgecine ，acyclovir ，vitamin B1 and vitamin B12，and con- trol group was given conventional treatment of acyclovir ，vitamin B1 and vitamin B12. The time of response and analgesia ，duration of lesion clearance and recovery time were observed in 2 groups. Pain visual analog scale （VAS ）evaluation was conducted before treatment ，3，7 and 10days after treatment. The adverse drug reaction in the treatment were observed. RESULTS ：The time of re- sponse and analgesia ，duration of lesion clearance and recovery time in