Complementary Role of HCV and HIV in T-Cell Activation and Exhaustion in HIVHCV Coinfection.docVIP

ComplementaryRoleofHCVandHIVinT-CellActivation andExhaustioninHIV/HCVCoinfection ThijsFeuth1,JoopE.Arends1,JustinH.Fransen1,2,NeningM.Nanlohy2,KarelJ.vanErpecum3, PeterD.Siersema3,AndyI.M.Hoepelman1,DebbievanBaarle1,2* 1DepartmentofInternalMedicineandInfectiousDiseases,UniversityMedicalCenterUtrecht(UMCU),Utrecht,TheNetherlands,2DepartmentofImmunology,University MedicalCenterUtrecht(UMCU),Utrecht,TheNetherlands,3DepartmentofGastroenterologyandHepatology,UniversityMedicalCenterUtrecht(UMCU),Utrecht,The Netherlands Abstract Objectives:ToinvestigatewhetherT-cellactivationandexhaustionislinkedto