Three-dimensional quantitative structure activity relationship (QSAR) of cytotoxic active 3,5-diaryl-4,5-dihydropyrazole analogs a comparative molecular field analysis (CoMFA) revisited study 英文论文文献.docVIP

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Three-dimensional quantitative structure activity relationship (QSAR) of cytotoxic active 3,5-diaryl-4,5-dihydropyrazole analogs a comparative molecular field analysis (CoMFA) revisited study 英文论文文献.doc

Three-dimensional quantitative structure activity relationship (QSAR) of cytotoxic active 3,5-diaryl-4,5-dihydropyrazole analogs a comparative molecular field analysis (CoMFA) revisited study 英文论文文献

HamadElgazwyetal.ChemistryCentralJournal2012,6:50 /content/6/1/50 RESEARCH ARTICLE OpenAccess Three-dimensionalquantitativestructureactivity relationship(QSAR)ofcytotoxicactive3,5-diaryl- 4,5-dihydropyrazoleanalogs:acomparative molecularfieldanalysis(CoMFA)revisitedstudy Abdel-SattarSHamadElgazwy1*,DaliaHSSoliman2,SaadRAtta-Allah1andDiaaAIbrahim3 Abstract Invitroantitumorevaluationofthesynthesized46compoundsof3,5-diaryl-4,5-dihydropyrazolesagainstEACcell linesand3DQSARstudyusingpharmacophoreandComparativeMolecularFieldAnalysis(CoMFA)methodswere described.CoMFAderivedQSARmodelshowsagoodconve

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