Thyroid hormone receptor actions on transcription in amphibia The roles of histone modification and chromatin disruption 英文论文文献.docVIP
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Thyroid hormone receptor actions on transcription in amphibia The roles of histone modification and chromatin disruption 英文论文文献
Shietal.CellBioscience2012,2:42
/content/2/1/42
Cell Bioscience
REVIEW
OpenAccess
Thyroidhormonereceptoractionson
transcriptioninamphibia:Therolesofhistone
modificationandchromatindisruption
Yun-BoShi1*,KazuoMatsuura1,KentaFujimoto2,LuanWen1andLiezhenFu1
Abstract
Thyroidhormone(T3)playsdiverserolesinadultorganfunctionandduringvertebratedevelopment.Themost
importantstageofmammaliandevelopmentaffectedbyT3istheperinatalperiodwhenplasmaT3levelpeaks.
AmphibianmetamorphosisresemblesthismammalianpostembryonicperiodandisabsolutelydependentonT3.
Theabilitytoeasilymanipulatethisprocessmakesitanidealm
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