Thyroid hormone receptor actions on transcription in amphibia The roles of histone modification and chromatin disruption 英文论文文献.docVIP

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Thyroid hormone receptor actions on transcription in amphibia The roles of histone modification and chromatin disruption 英文论文文献.doc

Thyroid hormone receptor actions on transcription in amphibia The roles of histone modification and chromatin disruption 英文论文文献

Shietal.CellBioscience2012,2:42 /content/2/1/42 Cell Bioscience REVIEW OpenAccess Thyroidhormonereceptoractionson transcriptioninamphibia:Therolesofhistone modificationandchromatindisruption Yun-BoShi1*,KazuoMatsuura1,KentaFujimoto2,LuanWen1andLiezhenFu1 Abstract Thyroidhormone(T3)playsdiverserolesinadultorganfunctionandduringvertebratedevelopment.Themost importantstageofmammaliandevelopmentaffectedbyT3istheperinatalperiodwhenplasmaT3levelpeaks. AmphibianmetamorphosisresemblesthismammalianpostembryonicperiodandisabsolutelydependentonT3. Theabilitytoeasilymanipulatethisprocessmakesitanidealm

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