Tissue distribution of cloxacillin after intramammary administration in the isolated perfused bovine udder 英文论文文献.docVIP
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Tissue distribution of cloxacillin after intramammary administration in the isolated perfused bovine udder 英文论文文献
Kietzmannetal.BMCVeterinaryResearch2010,6:46
/1746-6148/6/46
RESEARCH ARTICLE
OpenAccess
Tissuedistributionofcloxacillinafter
intramammaryadministrationintheisolated
perfusedbovineudder
ManfredKietzmann1*,FrankNiedorf1,JacquesGossellin2
Abstract
Background:Variousintramammarysuspensionscontainingcloxacillinbenzathineareregisteredforuseincattle
asantibioticsforintramammaryuseatdryingoff.Toensureantibacterialefficacy,theglandulartissue
concentrationofanantimicrobialagentmustbesufficient.Sincethepossibilitiestomeasureconcentrationsinthe
differentareasoftheglandulartissueinvivoareverylimited,it
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