Tobramycin at subinhibitory concentration inhibits the RhlIR quorum sensing system in a Pseudomonas aeruginosa environmental isolate 英文论文文献.docVIP
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Tobramycin at subinhibitory concentration inhibits the RhlIR quorum sensing system in a Pseudomonas aeruginosa environmental isolate 英文论文文献
Babi?etal.BMCInfectiousDiseases2010,10:148
/1471-2334/10/148
RESEARCH ARTICLE
OpenAccess
Tobramycinatsubinhibitoryconcentration
inhibitstheRhlI/Rquorumsensingsystemina
Pseudomonasaeruginosaenvironmentalisolate
FedoraBabi?1,2,VittorioVenturi2*,GordanaMaravi?-Vlahovi?ek1*
Abstract
Background:Antibioticsarenotonlysmallmoleculeswiththerapeuticactivityinkillingorinhibitingmicrobial
growth,butcanalsoactassignalingmoleculesaffectinggeneexpressioninbacterialcommunities.Afewstudies
havedemonstratedtheeffectoftobramycinasasignalmoleculeongeneexpressionatthetranscriptionallevel
anditseffectonbacterial
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