Topological characterisation and identification of critical domains within glucosyltransferase IV (GtrIV) of Shigella flexneri 英文论文文献.docVIP

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Topological characterisation and identification of critical domains within glucosyltransferase IV (GtrIV) of Shigella flexneri 英文论文文献.doc

Topological characterisation and identification of critical domains within glucosyltransferase IV (GtrIV) of Shigella flexneri 英文论文文献

Nairetal.BMCBiochemistry2011,12:67 /1471-2091/12/67 RESEARCH ARTICLE OpenAccess Topologicalcharacterisationandidentificationof criticaldomainswithinglucosyltransferaseIV (GtrIV)ofShigellaflexneri AneshNair,HaralambosKorresandNareshKVerma* Abstract Background:ThethreebacteriophagegenesgtrA,gtrBandgtr(type) areresponsibleforO-antigenglucosylationin Shigellaflexneri.BothgtrAandgtrBhavebeendemonstratedtobehighlyconservedandinterchangeableamong serotypeswhilegtr(type) wasfoundtobespecifictoeachserotype,leadingtothehypothesisthattheGtr(type) proteinsareresponsibleforattachingglucosylgroupsto

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