Topological characterisation and identification of critical domains within glucosyltransferase IV (GtrIV) of Shigella flexneri 英文论文文献.docVIP
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Topological characterisation and identification of critical domains within glucosyltransferase IV (GtrIV) of Shigella flexneri 英文论文文献
Nairetal.BMCBiochemistry2011,12:67
/1471-2091/12/67
RESEARCH ARTICLE
OpenAccess
Topologicalcharacterisationandidentificationof
criticaldomainswithinglucosyltransferaseIV
(GtrIV)ofShigellaflexneri
AneshNair,HaralambosKorresandNareshKVerma*
Abstract
Background:ThethreebacteriophagegenesgtrA,gtrBandgtr(type) areresponsibleforO-antigenglucosylationin
Shigellaflexneri.BothgtrAandgtrBhavebeendemonstratedtobehighlyconservedandinterchangeableamong
serotypeswhilegtr(type) wasfoundtobespecifictoeachserotype,leadingtothehypothesisthattheGtr(type)
proteinsareresponsibleforattachingglucosylgroupsto
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