TRAIL and vitamins opting for keys to castle of cancer proteome instead of open sesame 英文论文文献.docVIP

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TRAIL and vitamins opting for keys to castle of cancer proteome instead of open sesame 英文论文文献.doc

TRAIL and vitamins opting for keys to castle of cancer proteome instead of open sesame 英文论文文献

Farooqietal.CancerCellInternational2012,12:22 /content/12/1/22 REVIEW OpenAccess TRAILandvitamins:optingforkeystocastleof cancerproteomeinsteadofopensesame AmmadAhmadFarooqi1*,ShahzadBhatti2andMuhammadIsmail3 Abstract Cancerisamultifacetedmoleculardisorderthatismodulatedbyacombinationofgenetic,metabolicandsignal transductionaberrations,whichseverelyimpairthenormalhomeostasisofcellgrowthanddeath.Accumulating findingshighlightthefactthatdifferentgeneticalterations,suchasmutationsintumorsuppressorgenes,mightbe relatedtodistinctanddifferentialsensitivitytotargetedtherapies.Itisbecomingincreasing

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