TP53 mutation p.R337H in gastric cancer tissues of a 12-year-old male child - evidence for chimerism involving a common mutant founder haplotype case report 英文论文文献.docVIP

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TP53 mutation p.R337H in gastric cancer tissues of a 12-year-old male child - evidence for chimerism involving a common mutant founder haplotype case report 英文论文文献.doc

TP53 mutation p.R337H in gastric cancer tissues of a 12-year-old male child - evidence for chimerism involving a common mutant founder haplotype case report 英文论文文献

daSilvaetal.BMCCancer2011,11:449 /1471-2407/11/449 CASE REPORT OpenAccess TP53mutationp.R337Hingastriccancertissues ofa12-year-oldmalechild-evidencefor chimerisminvolvingacommonmutantfounder haplotype:casereport EdaiseMdaSilva1,MariaIsabelWAchatz1,GhyslaineMartel-Planche2,AndréLMontagnini3,MagaliOlivier2, PatriciaAProlla4,PierreHainaut2*andFernandoASoares1 Abstract Background:Gastricadenocarcinomaisrareinchildrenandadolescents,withabout17casesunderage21inthe world’sliterature.Wereportacaseofinvasivewell-differentiatedmetastaticgastriccancerinaBrazilian12-year-old boywithoutdocumentedfamilialhi

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