ToxR of Vibrio cholerae affects biofilm, rugosity and survival with Acanthamoeba castellanii 英文论文文献.docVIP

Valeruetal.BMCResearchNotes2012,5:33 /1756-0500/5/33 RESEARCH ARTICLE OpenAccess ToxRofVibriocholeraeaffectsbiofilm,rugosity andsurvivalwithAcanthamoebacastellanii SoniPValeru1,SunNWai2,AmirSaeed1,GunnarSandstr?m1andHadiAbd1* Abstract Background:Vibriocholeraecausesthediarrhealdiseasecholeraandutilizesdifferentsurvivalstrategiesinaquatic environments.V.choleraecansurviveasfree-livingorinassociationwithzooplanktonandcanbuildbiofilmand rugosecolonies.Thebacteriumexpressescholeratoxin(CT)andtoxin-coregulatedpilus(TCP)asthemain virulencefactors.Thesefactorsareco-regulatedbyatranscriptionalregul