Transcribed-ultra conserved region expression profiling from low-input total RNA 英文论文文献.docVIP
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Transcribed-ultra conserved region expression profiling from low-input total RNA 英文论文文献
Scaruffietal.BMCGenomics2010,11:149
/1471-2164/11/149
METHODOLOGY ARTICLE
OpenAccess
Transcribed-ultraconservedregionexpression
profilingfromlow-inputtotalRNA
PaolaScaruffi1*,SaraStigliani1,SimonaCoco1,FranscescaValdora2,CarlaDeVecchi1,StefanoBonassi3,
GianPaoloTonini1
Abstract
Background:UltraConservedRegions(UCRs)areaclassof481noncodingsequenceslocatedinbothintra-and
inter-genicregionsofthegenome.Therecentfindingsthattheyaresignificantlyalteredinadultchronic
lymphocyticleukemias,carcinomas,andpediatricneuroblastomasleadtothehypothesisthatUCRsmayplayarole
intumorigenesis.
Results:Wepresent
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