Transcriptional regulation of respiration in yeast metabolizing differently repressive carbon substrates 英文论文文献.docVIP

FendtandSauerBMCSystemsBiology2010,4:12 /1752-0509/4/12 RESEARCH ARTICLE OpenAccess Transcriptionalregulationofrespirationin yeastmetabolizingdifferentlyrepressive carbonsubstrates Sarah-MariaFendt1,2,3,UweSauer1,3* Abstract Background:Dependingonthecarbonsource,Saccharomycescerevisiaedisplaysvariousdegreesofrespiration. Theserangefromcompleterespirationasinthecaseofethanol,toalmostcompletefermentation,andthusvery lowdegreesofrespirationonglucose.Whilemanykeyregulatorsareknownfortheseextremecases,wefocus hereonregulatorsthatarerelevantatintermediatelevelsofrespiration. Results:Weaddressthis