Transcriptional regulation of gene expression clusters in motor neurons following spinal cord injury 英文论文文献.docVIP

Ryge et al. BMC Genomics 2010, 11:365 /1471-2164/11/365 RESEARCH ARTICLE Open Access Transcriptional regulation of gene expression Research article clusters in motor neurons following spinal cord injury Jesper Ryge*1, Ole Winther2,3, Jacob Wienecke4, Albin Sandelin2, Ann-Charlotte Westerdahl1, Hans Hultborn4 and Ole Kiehn*1 Abstract Background: Spinal cord injury leads to neurological dysfunctions affecting the motor, sensory as well as the autonomic systems. Increased excitability of motor neurons has been implicated in injury-induced spasticity, where the reappearance of self-susta