Transcriptome and proteome analysis of tyrosine kinase inhibitor treated canine mast cell tumour cells identifies potentially kit signaling-dependent genes 英文论文文献.docVIP

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Transcriptome and proteome analysis of tyrosine kinase inhibitor treated canine mast cell tumour cells identifies potentially kit signaling-dependent genes 英文论文文献.doc

Transcriptome and proteome analysis of tyrosine kinase inhibitor treated canine mast cell tumour cells identifies potentially kit signaling-dependent genes 英文论文文献

Klopfleischetal.BMCVeterinaryResearch2012,8:96 /1746-6148/8/96 RESEARCH ARTICLE OpenAccess Transcriptomeandproteomeanalysisof tyrosinekinaseinhibitortreatedcanine mastcelltumourcellsidentifiespotentially kitsignaling-dependentgenes RobertKlopfleisch1*,AnjaMeyer1,PatriciaSchlieben1,AngelikaBondzio2,ChrisWeise3,DidoLenze4, MichaelHummel4,RalfEinspanier2andAchimDGruber1 Abstract Background:CaninemastcelltumourproliferationdependstoalargeextentontheactivityofKIT,atyrosine kinasereceptor.InhibitorsoftheKITtyrosinekinasehaverecentlybeenintroducedandsuccessfullyappliedasa therapeuticagentforthistu

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