Transcriptomic analysis of the temporal host response to skin infestation with the ectoparasitic mite Psoroptes ovis 英文论文文献.docVIP
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Transcriptomic analysis of the temporal host response to skin infestation with the ectoparasitic mite Psoroptes ovis 英文论文文献
Burgessetal.BMCGenomics2010,11:624
/1471-2164/11/624
RESEARCH ARTICLE
OpenAccess
Transcriptomicanalysisofthetemporalhost
responsetoskininfestationwiththe
ectoparasiticmitePsoroptesovis
StewartTGBurgess*,DavidFrew,FrancescaNunn,CraigAWatkins,TomNMcNeilly,
AlasdairJNisbet,JohnFHuntley
Abstract
Background:InfestationofovineskinwiththeectoparasiticmitePsoroptesovisresultsinarapidcutaneous
immuneresponse,leadingtothecrustedskinlesionscharacteristicofsheepscab.Littleisknownregardingthe
mechanismsbywhichsuchaprofoundinflammatoryresponseisinstigatedandtoidentifynovelvaccineanddrug
targetsabetterund
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