Transcriptional profiling of ErbB signalling in mammary luminal epithelial cells - interplay of ErbB and IGF1 signalling through IGFBP3 regulation 英文论文文献.docVIP

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Transcriptional profiling of ErbB signalling in mammary luminal epithelial cells - interplay of ErbB and IGF1 signalling through IGFBP3 regulation 英文论文文献.doc

Transcriptional profiling of ErbB signalling in mammary luminal epithelial cells - interplay of ErbB and IGF1 signalling through IGFBP3 regulation 英文论文文献

Worthingtonetal.BMCCancer2010,10:490 /1471-2407/10/490 RESEARCH ARTICLE OpenAccess TranscriptionalprofilingofErbBsignallingin mammaryluminalepithelialcells-interplayof ErbBandIGF1signallingthroughIGFBP3 regulation JennyWorthington1?,MarianaBertani2?,Hong-LinChan3,BertranGerrits2,JohnFTimms1* Abstract Background:MembersoftheErbBfamilyofgrowthfactorreceptorsareintricatelylinkedwithepithelialcell biology,developmentandtumourigenesis;however,themechanismsinvolvedintheirdownstreamsignallingare poorlyunderstood.Indeed,itisunclearhowsignalspecificityisachievedandtherelativecontributioneach recepto

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