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Trans-generational epigenetic regulation of C. elegans primordial germ cells 英文论文文献
Furuhashietal.EpigeneticsChromatin2010,3:15
/content/3/1/15
RESEARCH
OpenAccess
Trans-generationalepigeneticregulationof
C.elegansprimordialgermcells
HirofumiFuruhashi1,4,TeruakiTakasaki2,AndreasRechtsteiner2,TengguoLi1,HiroshiKimura3,PaulaMChecchi1,5,
SusanStrome2,WilliamGKelly1*
Abstract
Background:Theprocessesthroughwhichthegermlinemaintainsitscontinuityacrossgenerationshaslongbeen
thefocusofbiologicalresearch.Recentstudieshavesuggestedthatgermlinecontinuitycaninvolveepigenetic
regulation,includingregulationofhistonemodifications.However,itisnotclearhowhistonemodifications
generatedinoneg
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