Tracking human multiple myeloma xenografts in NOD-Rag-1IL-2 receptor gamma chain-null mice with the novel biomarker AKAP-4 英文论文文献.docVIP
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Tracking human multiple myeloma xenografts in NOD-Rag-1IL-2 receptor gamma chain-null mice with the novel biomarker AKAP-4 英文论文文献
Mirandolaetal.BMCCancer2011,11:394
/1471-2407/11/394
RESEARCH ARTICLE
OpenAccess
Trackinghumanmultiplemyelomaxenograftsin
NOD-Rag-1/IL-2receptorgammachain-nullmice
withthenovelbiomarkerAKAP-4
LeonardoMirandola1,2?,YuefeiYu1?,MarjorieRJenkins1,2,3,RaffaellaChiaramonte1,4,EverardoCobos1,2,
ConstanceMJohn5andMaurizioChiriva-Internati1,2*
Abstract
Background:Multiplemyeloma(MM)isafatalmalignancyrankingsecondinprevalenceamonghematological
tumors.Continuouseffortsarebeingmadetodevelopinnovativeandmoreeffectivetreatments.Thepreclinical
evaluationofnewtherapiesreliesontheuseofmurinemodelsofthedisea
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