Transcriptomic effects of di-(2-ethylhexyl)-phthalate in Syrian hamster embryo cells an important role of early cytoskeleton disturbances in carcinogenesis 英文论文文献.docVIP
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Transcriptomic effects of di-(2-ethylhexyl)-phthalate in Syrian hamster embryo cells an important role of early cytoskeleton disturbances in carcinogenesis 英文论文文献
Landkoczetal.BMCGenomics2011,12:524
/1471-2164/12/524
RESEARCH ARTICLE
OpenAccess
Transcriptomiceffectsofdi-(2-ethylhexyl)-
phthalateinSyrianhamsterembryocells:an
importantroleofearlycytoskeletondisturbances
incarcinogenesis?
YannLandkocz1*,PascalPoupin1,FranckAtienzar2andPauleVasseur1
Abstract
Background:Di-(2-ethylhexyl)-phthalate(DEHP)isacommonlyusedplasticizerinpolyvinylchloride(PVC)
formulationsandapotentiallynon-genotoxiccarcinogen.Theaimofthisstudywastoidentifygeneswhoselevel
ofexpressionisalteredbyDEHPbyusingaglobalwide-genomeapproachinSyrianhamsterembryo(SHE)cells,a
modelsimilartoh
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