原创力文档Transcripts with in silico predicted RNA structure are enriched everywhere in the mouse brain 英文论文文献.docVIP
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Transcripts with in silico predicted RNA structure are enriched everywhere in the mouse brain 英文论文文献
Seemannetal.BMCGenomics2012,13:214
/1471-2164/13/214
RESEARCH ARTICLE
OpenAccess
TranscriptswithinsilicopredictedRNA
structureareenrichedeverywhereinthe
mousebrain
StefanESeemann1,2,SusanMSunkin3,MichaelJHawrylycz3,WalterLRuzzo1,4,5andJanGorodkin1,2*
Abstract
Background: Post-transcriptionalcontrolofgeneexpressionismostlyconductedbyspeci?celementsin
untranslatedregions(UTRs)ofmRNAs,incollaborationwithspeci?cbindingproteinsandRNAs.Inseveralwell
characterizedcases,theseRNAelementsareknowntoformstablesecondarystructures.RNAsecondarystructuresalso
mayhavemajorfunctionalimplicationsforlongnoncod
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