Transcriptome analysis of a long-lived natural Drosophila variant a prominent role of stress- and reproduction-genes in lifespan extension 英文论文文献.docVIP
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Transcriptome analysis of a long-lived natural Drosophila variant a prominent role of stress- and reproduction-genes in lifespan extension 英文论文文献
Doroszuketal.BMCGenomics2012,13:167
/1471-2164/13/167
RESEARCH ARTICLE
OpenAccess
Transcriptomeanalysisofalong-livednatural
Drosophilavariant:aprominentroleofstress-and
reproduction-genesinlifespanextension
AgnieszkaDoroszuk1*,MartijsJJonker2,3,NicolienPul1,TimoMBreit2,3andBasJZwaan1,4
Abstract
Background:Whilestudyinglong-livedmutantshasadvancedourunderstandingoftheprocessesinvolvedin
ageing,themechanismsunderlyingnaturalvariationinlifespanandageingrateremainlargelyunknown.Here,we
characterisegenome-wideexpressionpatternsofalong-lived,naturalvariantofDrosophilamelanogasterresulting
fromsel
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