Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi 英文论文文献.docVIP
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Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi 英文论文文献
Lietal.BMCGenomics2012,13:184
/1471-2164/13/184
RESEARCH ARTICLE
OpenAccess
Transcriptionprofilingrevealsstage-and
function-dependentexpressionpatternsinthe
filarialnematodeBrugiamalayi
Ben-WenLi1,4*,ZhengyuanWang2,AmyCRush1,MakedonkaMitreva2,3andGaryJWeil1
Abstract
Background:Brugiamalayiisanematodeparasitethatcauseslymphaticfilariasis,adisfiguringanddisabiling
tropicaldisease.Althoughafirstdraftgenomesequencewasreleasedin2007,verylittleisunderstoodabout
transcriptionprogramsthatgoverndevelopmentalchangesrequiredfortheparasite’sdevelopmentandsurvivalin
itsmammalianandinsecthosts.
Results:W
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