TRAIL receptor I (DR4) polymorphisms C626G and A683C are associated with an increased risk for hepatocellular carcinoma (HCC) in HCV-infected patients 英文论文文献.docVIP
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TRAIL receptor I (DR4) polymorphisms C626G and A683C are associated with an increased risk for hepatocellular carcinoma (HCC) in HCV-infected patients 英文论文文献
K?rneretal.BMCCancer2012,12:85
/1471-2407/12/85
RESEARCH ARTICLE
OpenAccess
TRAILreceptorI(DR4)polymorphismsC626Gand
A683Careassociatedwithanincreasedriskfor
hepatocellularcarcinoma(HCC)inHCV-infected
patients
ChristianK?rner1,KatarinaRiesner1,BenjaminKr?mer1,MarianneEisenhardt1,AndreasGl?ssner1,FranziskaWolter1,
ThomasBerg2,TobiasMüller3,TilmanSauerbruch1,JacobNattermann1,UlrichSpengler1and
HansDieterNischalke1*
Abstract
Background:TumoursurveillanceviainductionofTRAIL-mediatedapoptosisisakeymechanism,howthe
immunesystempreventsmalignancy.TodetermineifgenevariantsintheTRAILreceptorI(DR4)gene
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