Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling 英文论文文献.docVIP

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Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling 英文论文文献.doc

Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling 英文论文文献

DayandBeckBMCDevelopmentalBiology2011,11:54 /1471-213X/11/54 RESEARCH ARTICLE OpenAccess Transdifferentiationfromcorneatolensin XenopuslaevisdependsonBMPsignallingand involvesupregulationofWntsignalling RobertCDay1,2 andCarolineWBeck1,3* Abstract Background:SurgicalremovalofthelensfromlarvalXenopuslaevisresultsinarapidtransdifferentionofcentral cornealcellstoformanewlens.Thetriggerforthisprocessisunderstoodtobeaninductioneventarisingfrom theunprecedentedexposureofthecorneatothevitreoushumourthatoccursfollowinglensremoval.The molecularidentityofthistriggerisunknown. Results:Here,wehaveusedafu

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