Transforming growth factor-beta and breast cancer Introduction 英文论文文献.docVIP

/content/2/2/091 Review Transforming growth factor-β and breast cancer Introduction Joyce Slingerland Sunnybrook and Women’s College Health Sciences Centre, Toronto, Ontario, Canada Received: 7 February 2000 Accepted: 7 February 2000 Published: 21 February 2000 Breast Cancer Res 2000, 2:91 ? Current Science Ltd The balance between growth stimulatory and growth inhibitory signals is essential for normal tissue homeosta- sis. An imbalance of these signals may favour the devel- Mechanisms of G arrest by TGF-β and their dysregula- 1 tion in cancers are addressed. In