原创力文档Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure 英文论文文献.docVIP
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Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure 英文论文文献
Giorgietal.BMCCellBiology2011,12:27
/1471-2121/12/27
METHODOLOGY ARTICLE
OpenAccess
Translocationofsignallingproteinstothe
plasmamembranerevealedbyanew
bioluminescentprocedure
CarlottaGiorgi1,2,3?,AnnaRomagnoli2?,ChiaraAgnoletto1,LedaBergamelli2,GiovanniSorrentino2,MarisaBrini4,
TullioPozzan5,6,JacopoMeldolesi3,PaoloPinton1* andRosarioRizzuto5*
Abstract
Background:ActivationbyextracellularligandsofGprotein-coupled(GPCRs)andtyrosinekinasereceptors(RTKs),
resultsinthegenerationofsecondmessengersthatinturncontrolspecificcellfunctions.Further,modulation/
amplificationorinhibitionoftheinitials
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