Transmission electron microscopy characterization of fluorescently labelled amyloid β 1-40 and α-synuclein aggregates 英文论文文献.docVIP

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Transmission electron microscopy characterization of fluorescently labelled amyloid β 1-40 and α-synuclein aggregates 英文论文文献.doc

Transmission electron microscopy characterization of fluorescently labelled amyloid β 1-40 and α-synuclein aggregates 英文论文文献

AndersonandWebbBMCBiotechnology2011,11:125 /1472-6750/11/125 RESEARCH ARTICLE OpenAccess Transmissionelectronmicroscopy characterizationoffluorescentlylabelledamyloid b1-40anda-synucleinaggregates ValerieLAndersonandWattWWebb* Abstract Background:Fluorescenttags,includingsmallorganicmoleculesandfluorescentproteins,enablethelocalization ofproteinmoleculesinbiomedicalresearchexperiments.However,theuseoftheselabelsmayinterferewiththe formationoflarger-scaleproteinstructuressuchasamyloidaggregates.Therefore,weinvestigatetheeffectsof somecommonlyusedfluorescenttagsonthemorphologiesoffibrilsgrown

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Transmission electron microscopy characterization of fluorescently labelled amyloid β 1-40 and α-synuclein aggregates 英文论文文献.docVIP