Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in a porcine ischemia-reperfusion model 英文论文文献.docVIP

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Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in a porcine ischemia-reperfusion model 英文论文文献.doc

Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in a porcine ischemia-reperfusion model 英文论文文献

vanderPalsetal.BMCCardiovascularDisorders2010,10:45 /1471-2261/10/45 RESEARCH ARTICLE OpenAccess TreatmentwiththeC5areceptorantagonist ADC-1004reducesmyocardialinfarctionina porcineischemia-reperfusionmodel JespervanderPals1,SashaKoul1,PatrikAndersson1,MatthiasG?tberg1,JoeyFAUbachs2,MikaelKanski2, H?kanArheden2,G?ranKOlivecrona1,BengtLarsson3,4,DavidErlinge1* Abstract Background:Polymorphonuclearneutrophils,stimulatedbytheactivatedcomplementfactorC5a,havebeen implicatedincardiacischemia/reperfusioninjury.ADC-1004isacompetitiveC5areceptorantagonistthathasbeen showntoinhibitcomplementrelatedn

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