Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment 英文论文文献.docVIP

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Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment 英文论文文献.doc

Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment 英文论文文献

Luetal.CardiovascularDiabetology2013,12 :28 /content/12/1/28 CARDIO VASCULAR DIABETOLOGY ORIGINAL INVESTIGATION OpenAccess Treatmentwithacopper-selectivechelatorcauses substantiveimprovementincardiacfunctionof diabeticratswithleft-ventricularimpairment JunLu1,8,BeauPontré3,4,StephenPickup7,SoonYChoong1,MingmingLi1,HongXu9,GregoryDGamble5, AnthonyRJPhillips1,2,6,BrettRCowan3,4,AlistairAYoung3,4andGarthJSCooper1,2,10,11,12* Abstract Background:Defectivecopperregulationisimplicatedasacausativemechanismoforgandamageindiabetes. Treatmentwithtrientine,adivalent-copper-selectivechelator,improvesa

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