Tubulin evolution in insects gene duplication and subfunctionalization provide specialized isoforms in a functionally constrained gene family 英文论文文献.docVIP

Nielsen et al. BMC Evolutionary Biology 2010, 10:113 /1471-2148/10/113 RESEARCH ARTICLE Open Access Tubulin evolution in insects: gene duplication and Research article subfunctionalization provide specialized isoforms in a functionally constrained gene family Mark G Nielsen*1, Sudhindra R Gadagkar1,2 and Lisa Gutzwiller1,3 Abstract Background: The completion of 19 insect genome sequencing projects spanning six insect orders provides the opportunity to investigate the evolution of important gene families, here tubulins. Tubulins are a family of eukaryotic structural genes that form mic