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Using context to improve protein domain identification 英文论文文献
Usingcontexttoimproveproteindomain
identification
Ochoaetal.
Ochoaetal.BMCBioinformatics2011,12:90
/1471-2105/12/90(31March2011)
Ochoaetal.BMCBioinformatics2011,12:90
/1471-2105/12/90
RESEARCH ARTICLE
OpenAccess
Usingcontexttoimproveproteindomain
identification
AlejandroOchoa1,3,ManuelLlinás1,3* andMonaSingh2,3*
Abstract
Background:Identifyingdomainsinproteinsequencesisanimportantstepinproteinstructuralandfunctional
annotation.Existingdomainrecognitionmethodstypicallyevaluateeachdomainpredictionindependentlyofthe
rest.However,themajorityofproteinsaremultidomain,andpairwisedomainco-occ
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